| 货号 | 2664/50 |
| 别名 | N-[3-(Dimethylamino)propyl]-N-[(eth |
| 供应商 | Tocris |
| 生物活性 | Selective D2-like dopamine receptor agonist (Ki values are 0.7, 1.5, 9.0 and 165 nM for D2, D3, D4 and D5 receptors respectively) that also displays high affinity for several serotonin receptor subtypes (Ki = 1.2 - 20.0 nM for 5-HT1A, 5-HT1D, 5-HT2A and 5-HT2B). Inhibits secretion of prolactin and growth hormone and reverses levodopa-induced dyskinesias in Parkinsonian monkeys. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 451.6 |
| 分子式 | C26H37N5O2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| CAS号 | 81409-90-7 |
| 参考文献 | Kvernmoet al (2006) A review of the receptor-binding and pharmacokinetic properties of dopamine agonists. Clin.Ther. 28 1065. PMID: 16982285. Hadj Taharet al (2000) Sustained cabergoline treatment reverses levodopa-induced dyskinesias in parkinsonian monkeys. Cin.Neuropharmacol. 23195. Eguchiet al (1995) Effect of cabergoline, a dopamine agonist, on estrogen-induced rat pituitary tumors:in vitro culture studies. Endocr.J. 42 413. PMID: 7670571. |