BPIPP (50 MG)
货号：
3635/50 基本售价：
12274.1 元 规格：
50 mg
产品信息
概述| 货号 | 3635/50 |
| 别名 | 5-(3-Bromophenyl)-5,11-dihydro-1,3-dimethyl-1H-indeno[2',1':5,6]pyrido[2,3-d]pyrimidine-2,4,6(3H)-trione |
性能| 供应商 | Tocris |
| 生物活性 | Non-competitive guanylyl cyclase (GC) and adenylyl cyclase (AC) inhibitor. Downregulates cAMP and cGMP synthesis, and suppresses cGMP accumulation in a variety of cell lines (IC50 = 3.4 - 11.2 μM). Inhibits GC-stimulated Cl-transportin vitro and suppresses toxin-induced intestinal fluid accumulation in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 450.28 |
| 分子式 | C22H16BrN3O3 |
| 可溶性/溶解性 | Soluble to 2 mM in DMSO |
| CAS号 | 325746-94-9 |
| 参考文献 | Kotset al (2008) Pyridopyrimidine derivatives as inhibitors of cyclic nucleotide synthesis: application for treatment of diarrhea. Proc.Natl.Acad.Sci.USA 1058440. |
