货号 | 1369/50 |
别名 | α-Methyl-3-methyl-4-phosphonophenylg |
供应商 | Tocris |
生物活性 | A selective group III mGlu receptor antagonist (apparent Kd values are 5.1 and 488 μM for group III and group II mGlu receptors respectively; IC50 > 1 mM for group I, NMDA, AMPA and kainate receptors). |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 259.2 |
分子式 | C10H14NO5P |
可溶性/溶解性 | Soluble to 100 mM in 1eq. NaOH |
参考文献 | Milleret al (2003) Phenylglycine derivatives as antagonists of group III metabotropic glutamate receptors expressed on neonatal rat primary afferent terminals. Br.J.Pharmacol. 139 1523. PMID: 12922940. Conwayet al (2001) Synthesis of phenylglycine derivatives as potent and selective antagonists of group III metabotropic glutamate receptors. Bioorg.Med.Chem.Lett. 11 777. PMID: 11277518. |