货号 | 1765/50 |
别名 | (αS)-α-Amino-3-[(4-carboxyphenyl)meth |
供应商 | Tocris |
生物活性 | AMPA and kainate receptor antagonist. Inhibits AMPA receptor-, but not kainate receptor-mediated currents on spinal neonatal motoneurons yet antagonizes kainate-induced responses on dorsal root C-fibres. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >98 % |
计算分子量 | 333.3 |
分子式 | C15H15N3O6 |
可溶性/溶解性 | Soluble to 100 mM in 1eq. NaOH and to 25 mM in 1eq. HCl |
CAS号 | 544697-47-4 |
参考文献 | Moreet al (2003) Structural requirements for novel willardiine derivatives acting as AMPA and kainate receptor antagonists. Br.J.Pharmacol. 138 1093. PMID: 12684265. Moreet al (2002) The novel antagonist 3-CBW discriminates between kainate receptors expressed on neonatal rat motoneurones and those on dorsal root C-fibres. Br.J.Pharmacol. 137 1125. PMID: 12429586. |