| 货号 | 0187/50 |
| 别名 | (±)-1-Aminocyclopentane-trans-1,3-di |
| 供应商 | Tocris |
| 生物活性 | Equimolecular mixture of (1S,3R)- and (1R,3S)-ACPD. Selective agonist for metabotropic glutamate receptors; active at both group I and group II mGlu receptors (EC50 values are 2, 15, 23 and ~800 μM at mGluR2, mGluR1, mGluR5 and mGluR4 respectively). (1S,3R)-ACPD (Cat. No. 0284) and cis-ACPD (Cat. No. 0186) also available. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 173.17 |
| 分子式 | C7H11NO4 |
| 可溶性/溶解性 | Soluble to 5 mM in water with gentle warming and to 50 mM in 1eq. NaOH |
| CAS号 | 67684-64-4 |
| 参考文献 | Contiet al (2002) Synthesis and pharmacology of 3-hydroxy-Δ2-isoxazoline-cyclopentance analogues of glutamic acid Farmaco 57 889. PMID: 12484537. Knopfelet al (1995) Metabotropic glutamate receptors: novel targets for drug development. J.Med.Chem. 38 1417. PMID: 7738999. Pin and Duvoisin (1995) The metabotropic glutamate receptors: structure and functions. Neuropharmacology 34 1. PMID: 7623957. Nakanishi (1992) Molecular diversity of glutamate receptors and implications for brain functions. Science 258 597. PMID: 1329206. |