TC-I 2000 (50 MG)
货号：
4632/50 基本售价：
11381.8 元 规格：
50 mg
产品信息
概述| 货号 | 4632/50 |
| 别名 | N-(4-Fluorophenyl)-3,4-dihydro-1-[4-(trifluoromethyl)phenyl]-2(1H)-isoquinolinecarboxamide |
性能| 供应商 | Tocris |
| 生物活性 | TRPM8 channel blocker. Inhibits icilin-induced TRPM8 channel activation in rTRPM8-expressing CHO cells (IC50 = 53 nM). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 414.4 |
| 分子式 | C23H18F4N2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 20 mM in ethanol |
| 参考文献 | Tamayoet al (2012) Fused piperidines as a novel class of potent and orally available transient receptor potential melastatin type 8 (TRPM8) antagonists. J.Med.Chem. 55 1593. PMID: 22329507. |
