TC-G 24 (50 MG)
货号：
4353/50 基本售价：
11381.8 元 规格：
50 mg
产品信息
概述| 货号 | 4353/50 |
| 别名 | N-(3-Chloro-4-methylphenyl)-5-(4-nitrophenyl)-1,3,4-oxadiazol-2-amine |
性能| 供应商 | Tocris |
| 生物活性 | Potent GSK-3β inhibitor (IC50 = 17 nM); displays selectivity for GSK-3β over CDK2 (22% inhibition at 10 μM). Increases liver glycogen reserves in rodents. Brain penetrant. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 330.73 |
| 分子式 | C15H11ClN4O3 |
| 可溶性/溶解性 | Soluble to 10 mM in DMSO with gentle warming |
| 参考文献 | Khanfaret al (2010) Discovery of novel GSK-3β inhibitors with potent in vitro and in vivo activities and excellent brain permeability using combined ligand- and structure-based virtual screening. J.Med.Chem. 53 8534. PMID: 21082766. |
