SW 033291 (50 MG)
货号:
5759/50 基本售价:
11381.8 元 规格:
50 mg
产品信息
概述货号 | 5759/50 |
别名 | 2-(Butylsulfinyl)-4-phenyl-6-(2-thienyl)-thieno[2,3-b]pyridin-3-amine |
性能供应商 | Tocris |
生物活性 | High affinity 15-hydroxyprostaglandin dehydrogenase (15-PGDH) inhibitor (Ki = 0.1 nM). Increases PGE2 levels in A549 cells in vitro, as well as in bone marrow, colon, lung and liver in mice. Promotes hematopoiesis, recovery from DSS-induced colitis, and hepatocyte proliferation after partial hepatectomy in mice. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >98 % |
计算分子量 | 412.59 |
分子式 | C21H20N2OS3< |
可溶性/溶解性 | Soluble to 100 mM in DMSO and to 20 mM in ethanol |
参考文献 | Zhanget al (2015) Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration. Science 345 aaa2340. PMID: 26068857. |