| 货号 | 0853/50 |
| 别名 | (RS)-α-Methyl-4-phosphonophenylglyci |
| 供应商 | Tocris |
| 生物活性 | Potent antagonist of L-AP4-induced effects in rat spinal cord, thalamic and hippocampal neurons, showing selectivity over (1S,3S)-ACPD-induced effects. Potent antagonist of mGlu receptors linked to adenylyl cyclase in adult rat cortical slices. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 245.17 |
| 分子式 | C9H12NO5P |
| 可溶性/溶解性 | Soluble to 100 mM in 1eq. NaOH |
| CAS号 | 169209-65-8 |
| 参考文献 | Bedingfieldet al (1996) Novel potent selective phenylglycine antagonists of metabotropic glutamate receptors. Eur.J.Pharmacol. 309 71. PMID: 8864696. Bushellet al (1996) Pharmacological antagonism of the actions of group II and group III mGluR agonists in the lateral perforant path of rat hippocampal slices. Br.J.Pharmacol. 117 1457. PMID: 8730739. Salt and Turner (1996) Antagonism of the presumed presynaptic action of L-AP4 on GABAergic transmission in the ventrobasal thalamus by the novel mGluR anatagonist MPPG. Neuropharmacology 35 239. PMID: 8734494. Janeet al (1995) New phenylglycine derivatives with potent and selective antagonist activity at presynaptic glutamate receptors in neonatal rat spinal cord. Neuropharmacology 34 851. PMID: 8532166. |