| 货号 | 3822/50 |
| 别名 | 6-[2-(5,6,7,8-Tetrahydro-5,5,8,8-te |
| 供应商 | Tocris |
| 生物活性 | Selective RARγ antagonist. Blocks the growth inhibitory ability of RARγ-selective agonists in squamous cell carcinoma (SCC)-25 cells. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 462.67 |
| 分子式 | C28H30O2S2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Dawsonet al (2001) Apoptosis induction in cancer cells by a novel analogue of 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalenecarboxylic acid lacking retinoid receptor transcriptional activation activity. Cancer Res. 61 4723. PMID: 11406543. Holmeset al (2000) Induction of apoptosis in ovarian carcinoma cells by AHPN/CD437 is mediated by retinoic acid receptors. J.Cell.Physiol. 185 61. PMID: 10942519. Leet al (2000) Modulation of retinoic acid receptor function alters the growth inhibitor response of oral SCC cells to retinoids. Oncogene 19 1457. PMID: 10723137. |