| 货号 | 4266/50 |
| 别名 | 4-[4,5-Dihydro-5-(4-methoxyphenyl)- |
| 供应商 | Tocris |
| 生物活性 | Allosteric inhibitor of Cdc42 GTPase (EC50 = 2.1 μM). Selective for Cdc42 over other members of the Rho GTPase family including Rac1, Rab2 and Rab7. Inhibits ovarian cancer cell migration in vitro. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 407.49 |
| 分子式 | C22H21N3O3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Honget al (2013) Characterization of a Cdc42 GTPase Inhibitor and its Use as a Molecular Probe. J.Biol.Chem. Epub. PMID: 23382385. Surviladzeet al (2010) A potent and selective inhibitor of Cdc42 GTPase. Probe Reports from the Molecular Libraries Program NBK5196. PMID: 21433396. |