| 货号 | 0742/50 |
| 别名 | trans-2-Carboxy-5,7-dichloro-4-phen |
| 供应商 | Tocris |
| 生物活性 | Very potent antagonist at the glycine-NMDA site. Also available as part of the NMDA Receptor - Glycine Site Tocriset™. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 380.23 |
| 分子式 | C17H15Cl2N3O3 |
| 可溶性/溶解性 | Soluble to 25 mM in DMSO and to 100 mM in ethanol |
| CAS号 | 139051-78-8 |
| 参考文献 | Stone (2000) Development and therapeutic potential of kynurenic acid and kynurenine derivatives for neuroprotection. TiPS 21 149. PMID: 10740291. Leesonet al (1992) 4-Amido-2-carboxytetrahydroquinolines. Structure-activity relationship for antagonism at the glycine site of the NMDA receptor. J.Med.Chem. 35 1954. PMID: 1534584. Leesonet al(1991)trans-2-Carboxy-4-substituted tetrahydroquinolines. Potent glycine-site NMDA receptor antagonists. Med.Chem.Res. 164. |