| 货号 | 4276/50 |
| 别名 | 7-Ethenyl-2-(3-fluoro-4-hydroxyphen |
| 供应商 | Tocris |
| 生物活性 | Potent ERβ agonist; displays >200-fold selectivity for ERβ over ERα(IC50 values are 5 and 1216 nM for human ERβ and ERα; 3.1 and 620 nM for rat ERβ and ERα; and 3.7 and 750 nM for mouse ERβ and ERαrespectively). |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >99 % |
| 计算分子量 | 271.24 |
| 分子式 | C15H10FNO3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| 参考文献 | Cvoroet al (2008) Selective estrogen receptor-γ agonists repress transcription of proinflammatory genes. J.Immunol. 180 630. PMID: 18097065. Malamaset al (2004) Design and synthesis of aryl diphenolic azoles as potent and selective estrogen receptor-β ligands. J.Med.Chem. 47 5021. PMID: 15456246. Harriset al (2003) Evaluaton of an estrogen receptor-β agonist in animal models of human disease. Endocrinology 144 4241. PMID: 14500559. |