| 货号 | 1820/50 |
| 别名 | (S)-(+)-Methyl 2-(4,5,6,7-tetrahydrothieno[3,2-c]p |
| 供应商 | Tocris |
| 生物活性 | Selective, high affinity P2Y12 receptor antagonist. Inhibits ADP-induced platelet aggregation and displays antithrombotic activity. Active enantiomer of (±)-clopidogrel hydrochloride (Cat. No. 2490). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 419.9 |
| 分子式 | C16H16ClNO2S.H |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 100 mM in DMSO |
| 参考文献 | Kugelgen (2006) Pharmacological profiles of cloned mammalian P2Y-receptor subtypes. Pharmacol.Ther. 110 415. PMID: 16257449. Savi and Herbert (2005) Clopidogrel and ticlopidine: P2Y12 adenosine diphosphate-receptor antagonists for the prevention of atherothrombosis. Semin.Thromb.Haemostas. 31174. Saviet al (2001) P2Y12, a new platelet ADP receptor, target of clopidogrel. Biochem.Biophys.Res.Comm. 283379. Reistet al (2000) Very low chiral inversion of clopidogrel in rats: a pharmacokinetic and mechanistic investigation. Drug Metab.Disp. 281405. |