| 货号 | 4352/50 |
| 别名 | 1,3-Dihydro-N,3,3-trimethyl-1-pheny |
| 供应商 | Tocris |
| 生物活性 | Selective noradrenalin re-uptake inhibitor; exhibits a high affinity for the human noradrenalin transporter (NET) against SERT and DAT (IC50 values are 0.79, 850 and 9300 nM for inhibition of monoamine uptake by NET, SERT and DAT respectively). Antidepressant. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 347.95 |
| 分子式 | C20H25NS.HCl |
| 可溶性/溶解性 | Soluble to 20 mM in water and to 100 mM in DMSO |
| 参考文献 | Schouet al (2006) Synthesis and positron emission tomography evaluation of three norepinephrine transporter radioligands: [C-11]desipramine, [C-11]talopram and [C-11]talsupram. Mol.Imaging Biol. 81. McConathyet al (2004) Synthesis and biological evaluation of [11C]talopram and [11C]talsupram: candidate PET ligands for the norepinephrine transporter. Nucl.Med.Biol. 31 (6) 705. PMID: 15246361. Rowlettet al (2004) Cocaine-like discriminative stimulus effects of heroin: modulation by selective monoamine transport inhibitors. J.Pharmacol.Exp.Ther. 310 342. PMID: 14985417. |