| 货号 | 17798-100mg |
| 描述 | Elvitegravir is a quinolone antibiotic that inhibits the integrase of HIV-1 (IC50 = 7.2 nM).1 It blocks the integration of HIV-1 cDNA through the inhibition of DNA strand transfer.2 Elvitegravir is used in combination with a pharmacoenhancer and nucleoside/nucleotide reverse transcriptase inhibitors to block HIV-1 replication in vivo.3,4 |
| 别名 | GS-9137;JTK-303; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Sato, M.,Motomura, T.,Aramaki, H., et al. Novel HIV-1 integrase inhibitors derived from quinolone antibiotics. Journal of Medicinal Chemistry 49(5), 1506-1508 (2006). 2.Shimura, K.,Kodama, E.,Sakagami, Y., et al. Broad antiretroviral activity and resistance profile of the novel human immunodeficiency virus integrase inhibitor elvitegravir. J.Virology 82(2), 764-774 (2008). 3.Messiaen, P.,Wensing, A.M.J.,Fun, A., et al. Clincal use of HIV integrase inhibitors: A systematic review and meta-analysis. PLoS One 8(1), 1-16 (2013). 4.Pandey, K.K. Critical appraisal of elvitegravir in the treatment of HIV-1/AIDS. HIV/AIDS - Research and Palliative Care 6, 81-90 (2014). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 447.9 |
| 分子式 | C23H23ClFNO5 |
| CAS号 | 697761-98-1 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |