货号 | 3050/50 |
别名 | 5-[(2R)-2-[[2-(2-Ethoxyphenoxy)ethy |
供应商 | Tocris |
生物活性 | Selectiveα1A-adrenoceptor antagonist (pKi values are 9.97, 9.64 and 8.86 for α1A,α1Bandα1D subtypes respectively). Decreases resting maximal urethral pressure with negligable effect on mean arterial blood pressure in vivo. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 444.97 |
分子式 | C20H28N2O5S.HCl |
可溶性/溶解性 | Soluble to 10 mM in water and to 100 mM in DMSO |
CAS号 | 106463-17-6 |
参考文献 | Ohtakeet al (2005) Effects of tamsulosin on resting urethral pressure and arterial blood pressure in anaesthetized female dogs. J.Pharm.Pharmacol. 58345. Taguchiet al (1997) Effects of tamsulosin metabolites at alpha-1 adrenoceptor subtypes. J.Pharmacol.Exp.Ther. 280 1. PMID: 8996174. Garcia-Sainzet al (1995) Alpha 1-adrenoceptor subtype selectivity of tamsulosin: studies using livers from different species. Eur.J.Pharmacol. 289 1. PMID: 7781702. |