| 货号 | 2988/50 |
| 别名 | N-[2,6-bis(1-Methylethyl)phenyl]-N'- |
| 供应商 | Tocris |
| 生物活性 | Acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor. Decreases cholesterol levels in the plasma and liver of diabetic-hypercholesterolemic rats. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 449.57 |
| 分子式 | C25H27N3O3S |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 228544-65-8 |
| 参考文献 | Adameovaet al (2007) The myocardial infarct size-limiting and antiarrhythmic effects of acyl-CoA: cholesterol acyltransferase inhibitor VULM 1457 protect the hearts of diabetic-hypercholesterolaemic rats against ischaemia/reperfusion injury both in vitroandin vivo. Eur.J.Pharmacol. 576 114. PMID: 17764671. Vojtassakovaet al (2007) Effect of VULM 1457, an ACAT inhibitor, on serum lipid levels and on real time red blood cell flow in diabetic and non-diabetic hamsters fed high cholesterol-lipid diet. Gen.Physiol.Biophys. 26 254. PMID: 18281742. Adameovaet al (2006) Protective effect of simvastatin and VULM 1457 in ischaemic-reperfused myocardium of the diabetic-hypercholesterolemic rats. Pharmazie 61 807. PMID: 17020164. |