Nebivolol hydrochloride (50 MG)
货号：
3517/50 基本售价：
10489.5 元 规格：
50 mg
产品信息
概述| 货号 | 3517/50 |
| 别名 | (±)-[2R*(1S*5S*(S*))]-α,α'-[Iminobis(methylene)bis(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol) |
性能| 供应商 | Tocris |
| 生物活性 | Highly selective β1-adrenoceptor antagonist (Ki values are 0.88, 20, 44, 700, 1160, 2400 and 4000 nM at β1, 5-HT1A,β2, 5-HT2,α1, H1 and D2 receptors respectively). Induces vasodilation via a nitric oxide- and cGMP-dependent mechanism (EC50 = 11.36 μM in renal arteries) and displays antihypertensive activity in vivo. GRK/β -arrestin biased agonist at the β2 adrenoceptor. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 441.9 |
| 分子式 | C22H25F2NO4.HCl |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 10 mM in ethanol |
| CAS号 | 152520-56-4 |
| 参考文献 | Ericksonet al (2013) The |
