| 货号 | 1305/50 |
| 别名 | 1,2,3,4-Tetrahydro-4-(3-hydroxyphen |
| 供应商 | Tocris |
| 生物活性 | Potent, cell-permeable, small molecule mitosis inhibitor that does not interact with tubulin. Arrests cells in mitosis and specifically inhibits the motility of the mitotic kinesin Eg5, a motor protein required for mitotic spindle formation and maintenance (IC50 = 14 μM). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 292.35 |
| 分子式 | C14H16N2O3S |
| 可溶性/溶解性 | Soluble to 20 mM in ethanol and to 100 mM in DMSO |
| CAS号 | 254753-54-3 |
| 参考文献 | Kapooret al (2000) Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5. J.Cell Biol. 150 975. PMID: 10973989. Mayeret al (1999) Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen. Science 286 971. PMID: 10542155. |