| 货号 | 5725/50 |
| 别名 | 4-Methoxy-N-[[3-(1-methylethyl)-5-i |
| 供应商 | Tocris |
| 生物活性 | High affinity and selective presynaptic choline transporter (CHT) inhibitor (Ki = 92 nM). Exhibits selectivity for CHT over dopamine, serotonin and noradrenalin transporters; acetylcholinesterase and cholineacetyltransferase; and a panel of 65 other GPCRs, ion channels and transporters. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 423.93 |
| 分子式 | C21H29N3O4 |
| 可溶性/溶解性 | Soluble to 10 mM in water with gentle warming and to 100 mM in DMSO |
| 参考文献 | Bollingeret al (2015) Synthesis and structure-activity relationships of a series of 4-methoxy-3-(piperidin-4-yl)oxy benzamides as novel inhibitors of the presynaptic choline transporter. Bioorg.Med.Chem.Lett. 25 1757. PMID: 25801932. Enniset al (2015) Identification and characterization of ML352: a novel, noncompetitive inhibitor of the presynaptic choline transporter. ACS Chem.Neurosci. 6 417. PMID: 25560927. |