ML 298 hydrochloride (50 MG)
货号：
4895/50 基本售价：
10489.5 元 规格：
50 mg
产品信息
概述| 货号 | 4895/50 |
| 别名 | 3,4-Difluoro-N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]benzamide hydrochloride |
性能| 供应商 | Tocris |
| 生物活性 | Selective inhibitor of phospholipase D2 (PLD2) (IC50 values are 355 and >20,000 nM for PLD2 and PLD1, respectively). Decreases invasive migration in U87-MG glioblastoma cells, without affecting cell viability. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 468.9 |
| 分子式 | C22H23F3N4 |
| 可溶性/溶解性 | Soluble to 25 mM in DMSO |
| 参考文献 | O'Reillyet al (2013) Development of dual PLD1/2 adn PLD2 selective inhibitors from a common 1,3,8-triazaspiro[4.5]decane core: discovery of ML298 and ML299 that decrease invasive migration in U87-MG glioblastoma cells. J.Med.Chem. 56 2695. PMID: 23445448. |
