| 货号 | 0111/50 |
| 别名 | (2S,3S,4R)-2-Carboxy-4-isopropyl-3- |
| 供应商 | Tocris |
| 生物活性 | EAAT2(GLT1)-selective non-transportable inhibitor of L-glutamate and L-aspartate uptake (Ki = 23 μM). 130-fold selective over EAAT1 and EAAT3 (Ki > 3 mM). Also available as part of the Excitatory Amino Acid Transporter Inhibitor Tocriset™. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 215.25 |
| 分子式 | C10H17NO4 |
| 可溶性/溶解性 | Soluble to 25 mM in water |
| CAS号 | 52497-36-6 |
| 参考文献 | Arrizaet al (1994) Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex. J.Neurosci. 14 5559. PMID: 7521911. Kanalet al (1994) The neuronal and epithelial high affinity glutamate transporter, insights into structure and mechanism of transport. J.Biol.Chem. 269 20599. PMID: 7914198. Munozet al (1987) Effects of dihydrokainic acid on extracellular amino acids and neuronal excitability in the in vivo rat hippocampus. Neuropharmacology 26 1. PMID: 2882438. |