TB 21007 (50 MG)
货号：
2905/50 基本售价：
10192.1 元 规格：
50 mg
产品信息
概述| 货号 | 2905/50 |
| 别名 | 6,7-Dihydro-3-[(2-hydroxyethyl)thio]-6,6-dimethyl-1-(2-thiazolyl)-benzo[c]thiophen-4(5H)-one |
性能| 供应商 | Tocris |
| 生物活性 | GABAA receptor inverse agonist selective for the α5-subtype (Ki values are 1.6, 16, 20 and 20 nM for α5,α2,α1 and α3 subtypes respectively). Brain penetrant; enhances cognitive performance in rats in the delayed matching-to-place morris water maze test following i.p. administration. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 339.5 |
| 分子式 | C15H17NO2S3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 25 mM in ethanol |
| CAS号 | 207306-50-1 |
| 参考文献 | Chamberset al (2003) Identification of a novel, selective GABA5 α5 receptor inverse agonist which enhances cognition. J.Med.Chem. 46 2227. PMID: 12747794. |
