N-Benzylacetamidine (hydrobromide)
货号：
13570-100mg 基本售价：
10192.0 元 规格：
100 mg
产品信息
概述| 货号 | 13570-100mg |
| 描述 | Of the different types of nitric oxide synthases (NOS), the inducible (iNOS) form contributes to inflammation and immune response while the constitutively-expressed endothelial (eNOS) enzyme plays important roles in regulating vascular tone. N-Benzylacetamidine is a potent inhibitor of iNOS (IC50 = 0.20 μM), with over 1,000-fold selectivity compared to eNOS (IC50 = 350 µM).1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Maccallini, C.,Patruno, A.,Besker, N., et al. Synthesis, biological evaluation, and docking studies of N-substituted acetamidines as selective inhibitors of inducible nitric oxide synthase. Journal of Medicinal Chemistry 52, 1481-1485 (2009).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 229.1 |
| 分子式 | C9H12N2 ?HBr |
| CAS号 | 186545-76-6 |
| 稳定性 | ≥ 2 years |
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