Toxin A from Clostridium difficile
货号：
19664-100ug 基本售价：
10150.0 元 规格：
100 ug
产品信息
概述| 货号 | 19664-100ug |
| 描述 | Toxin A from Clostridium difficile, also known as TcdA, is an enterotoxin that has glucosyltransferase and cysteine protease activities. It inactivates host Rho family GTPases by glucosylation, altering cytoskeletal structure, cell division, and cell-cell adhesion.1,2 Toxin A can induce activation of the inflammasome and apoptosis.3 While both toxin A and toxin B (Item No. 19665) inactivate Rho family GTPases, toxin A has a higher binding affinity for epithelial cell surface carbohydrates.2 |
| 别名 | TcdA; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Chen, S.,Sun, C.,Wang, H., et al. The role of rho GTPases in toxicity of Clostridium difficile toxins. Toxins (Basel) 7(12), 5254-5267 (2016).
2.Pruitt, R.N., and Lacy, D.B. Toward a structural understanding of Clostridium difficile toxins A and B. Front.Cell.Infect.Microbiol. 2(28), (2012).
3.Di Bella, S.,Ascenzi, P.,Siarakas, S., et al. Clostridium difficile toxins A and B: Insights into pathogenic properties and extraintestinal effects. Toxins (Basel) 8(5), (2016).
|
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | 2-8 |
| 纯度 | ≥80% (estimated by SDS-PAGE) |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
