| 货号 | 15377-5mg |
| 描述 | Venturicidin A is a macrolide antibiotic isolated from strains of Streptomyces.1 It is active against fungi in the genus Venturia which cause apple scab, as well as other fungi, but not against higher plants.1 Venturicidin A is also cytotoxic against trypanosomes (IC50 = 120-540 ng/ml) while being more than 25,000 times less effective against mammalian cells.2 It inhibits bacterial and mitochondrial ATP synthases.3,4 |
| 别名 | Aabomycin A1; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Rhodes, A.,Fantes, K.H.,Boothroyd, B., et al. Venturicidin: A new antifungal antibiotic of potential use in agriculture. Nature 192, 952-954 (1961). 2.Otoguro, K.,Ishiyama, A.,Namatame, M., et al. Selective and potent in vitro antitrypanosomal activities of ten microbial metabolites. J.Antibiot.(Tokyo) 61(6), 372-378 (2008). 3.Perlin, D.S.,Latchney, L.R. and Senior, A.E. Inhibition of Escherichia coli H+-ATPase by venturicidin, oligomycin and ossamycin. Biochim.Biophys.Acta. 807(3), 238-244 (1985). 4.Matsuno-Yagi, A. and Hatefi, Y. Studies on the mechanism of oxidative phosphorylation. ATP synthesis by submitochondrial particles inhibited at F0 by venturicidin and organotin compounds. The Journal of Biological Chemisty 268(9), 6168-6173 (1993). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 750 |
| 分子式 | C41H67NO11 |
| CAS号 | 33538-71-5 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |