| 货号 | 17400-1mg |
| 描述 | Urodilatin is a renal natriuretic peptide first isolated from human urine.1,2 It is derived from the same precursor as atrial natriuretic peptide in kidney tubular cells and secreted luminally.2 Urodilatin regulates sodium and water reabsorption in the kidney.2,3 While it is not normally found in the circulation, systemic administration of urodilatin has pharmacological effects on renal, cardiovascular, and pulmonary parameters in animals.2,4 |
| 别名 | ANP 95-126; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Gagelmann, M.,Hock, D. and Forssman, W.G. Urodilatin (CDD/ANP-95-126) is not biologically inactivated by a peptidase from dog kidney cortex membranes in contrast to atrial natriuretic peptide/cardiodilatin (α-hANP/CDD-99-126). FEBS Letters 233(2), 249-254 (1988). 2.Forssman, W.G.,Meyer, M. and Forssmann, K. The renal urodilatin system: Clinical implications. Cardiovascular Research 51(3), 450-462 (2001). 3.Goetz, K.,Drummer, C.,Zhu, J.L., et al. Evidence that urodilatin, rather than ANP, regulates renal sodium excretion. Journal of the American Society of Nephrology 1(6), 867-874 (1990). 4.Hamlyn, J.M. Natriuretic hormones, endogenous ouabain, and related sodium transport inhibitors. Front.Endocrinol.(Lausanne) 5, (2015). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 3506 |
| 分子式 | C145H234N52O44S3 |
| CAS号 | 115966-23-9 |
| 稳定性 | ≥ 2 years |
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