tetranor-PGDM lactone-d6
货号：
11213-100ug 基本售价：
10024.0 元 规格：
100 ug
产品信息
概述| 货号 | 11213-100ug |
| 描述 | tetranor-PGDM lactone-d6 contains six deuterium atoms at the 16, 16, 17, 17, 18 and 18 positions. It is intended for use as an internal standard for the quantification of tetranor-PGDM lactone by GC- or LC-mass spectrometry. PGD2 plays a pharmacological role in allergic and asthmatic anaphylaxis, normal physiological sleep and lowering of body temperature, as well as inhibits platelet aggregation and relaxes vascular smooth muscle.1 tetranor-PGDM is an abundant urinary metabolite of PGD2 that is detectable both in human and mouse and, as such, is used as a biomarker of PGD2biosynthesis.2 tetranor-PGDM lactone is a closed form of tetranor-PGDM. The formation of tetranor-PGDM lactone in biological samples has not been evaluated. |
| 别名 | tetranor-Prostaglandin D Metabolite lactone-d6; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Giles, H. and Leff, P. The biology and pharmacology of PGD2. Prostaglandins 35, 277-300 (1988).
2.Song, W.L.,Wang, M.,Ricciotti, E., et al. Tetranor PGDM, an abundant urinary metabolite reflects biosynthesis of prostaglandin D2 in mice and humans. The Journal of Biological Chemisty 283(2), 1179-1188 (2008).
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| 运输条件 | Dry ice in continental US; may vary elsewhere |
| 存放说明 | -80 |
| 纯度 | ≥99% deuterated forms (d1-d6) |
| 计算分子量 | 316.4 |
| 分子式 | C16H16D6O6 |
| 稳定性 | ≥ 6 months |
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