| 货号 | 3766/50 |
| 别名 | (3S,4aS,8aS)-N-(1,1-Dimethylethyl)d |
| 供应商 | Tocris |
| 生物活性 | Orally active human immunodeficiency virus protease inhibitor. Potently inhibits HIV-1 protease (Ki = 2 nM) in vitro. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 663.89 |
| 分子式 | C32H45N3O4S.CH4O3S |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| CAS号 | 159989-65-8 |
| 参考文献 | Gillset al (2007) Nelfinavir, a lead HIV protease inhibitor, is a broad-spectrum, anticancer agent that induces endoplasmic reticulum stress, autophagy and apoptosis in vitroandin vivo. Clin.Cancer Res. 135183. Paticket al (1996) Antiviral and resistance studies of AG1343, an orally bioavailable inhibitor of human immunodeficiency virus protease. Antimicrob.Agents Chemother. 40 29. PMID: 8787874. Shettyet al (1996) Preclinical pharmacokinetics and distribution to tissue of AG1343, an inhibitor of human immunodeficiency virus type 1 protease. Antimicrob.Agents Chemother. 40 110. PMID: 8787890. |