ML 161 (50 MG)
货号:
4570/50 基本售价:
9894.7 元 规格:
50 mg
产品信息
概述货号 | 4570/50 |
别名 | 2-Bromo-N-[3-[(1-oxobutyl)amino]phenyl]benzamide |
性能供应商 | Tocris |
生物活性 | Inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50 = 0.26 μM for the inhibition of platelet P-selectin expression on human platelets). Thought to act allosterically. Also inhibits thrombin-induced platelet activation. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >98 % |
计算分子量 | 361.23 |
分子式 | C17H17BrN2O2 |
可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
参考文献 | Dockendorffet al (2012) Discovery of 1,3-diaminobenzenes as selective inhibitors of platelet activation at the PAR1 receptor. ACS Med.Chem.Lett. 3 232. PMID: 22408714. |