| 货号 | 1244/50 |
| 别名 | 2-[2-[4-(4-Nitrobenzyloxy)phenyl]et |
| 供应商 | Tocris |
| 生物活性 | Potent, selective inhibitor of the reverse mode of the Na+/Ca2+ exchanger (IC50 = 0.7 μM). Also inhibits the mitochondrial Ca2+ uniporter (MCU; IC50 = 5.5 μM). Does not affect Na+-dependent transport systems or ionotropic glutamate receptors. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 427.49 |
| 分子式 | C16H17N3O3S.CH3SO3H |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 182004-65-5 |
| 参考文献 | Santo-Domingoet al (2007) The plasma membrane +/Ca2+ exchange inhibitor KB-R7943 is also a potent inhibitor of the mitochondrial Ca2+ uniporter. Br.J.Pharmacol. 151 647. PMID: 17471180. Schr |