| 货号 | 4088/50 |
| 别名 | 1-[1-(4-Fluorophenyl)-2,5-dimethyl- |
| 供应商 | Tocris |
| 生物活性 | Selective inhibitor of Usp14; inhibits the catalytic activity of proteasome-associated Usp14 in vitro(IC50 < 4 μM). Stimulates proteasome activity and substrate degradation. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 300.37 |
| 分子式 | C18H21FN2O |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 50 mM in ethanol |
| 参考文献 | Leeet al (2010) Enhancement of proteasome activity by a small-molecule inhibitor of USP14. Nature 467 179. PMID: 20829789. Leeet al (2010) Trimming of ubiquitin chains by proteasome-associated deubiquitinating enzymes. Mol.Cell.Proteomics 10 R110. PMID: 20823120. |