| 货号 | 3961/50 |
| 别名 | 4-Chloro-N-[2-[[5-(trifluoromethyl) |
| 供应商 | Tocris |
| 生物活性 | Potent and selective peroxisome proliferator-activated receptor δ(PPARδ) antagonist (pIC50 = 6.6). Displays no measurable affinity for PPARα or PPARγin vitro(pIC50< 5). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 392.78 |
| 分子式 | C15H12ClF3N2O3S |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 188591-46-0 |
| 参考文献 | Palkaret al (2010) Cellular and pharmacological selectivity of the peroxisone proliferator-activated receptor-β/δ antagonist GSK3787. Mol.Pharmacol. 78 419. PMID: 20516370. Sheareret al (2010) Identification and characterization of 4-chloro-N(2-{[5-trifluoromethyl)-2-pyridyl]sulfonyl}ethyl)benzamide (GSK3787), a selective and irreversible peroxisome proliferator-activated receptor delta (PPARdelta) antagonist. J.Med.Chem. 53 1857. PMID: 20128594. |