| 货号 | 1425/50 |
| 别名 | N,N-Dimethyl-3-[(1S)-1-(2-pyridinyl |
| 供应商 | Tocris |
| 生物活性 | Enantiomer that is a subtype-selective M2 muscarinic receptor antagonist (pKi values are 7.08, 7.78, 6.70 and 7.00 for M1, M2, M3 and M4 receptors respectively). Also H1 histamine receptor antagonist (pKi = 7.48). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 408.5 |
| 分子式 | C20H24N2.C4H4O4 |
| 可溶性/溶解性 | Soluble to 100 mM in water with gentle warming |
| CAS号 | 121367-05-3 |
| 参考文献 | Lambrechtet al (1999) Neuronal soma-dendritic and prejunctional M1-M4 receptors in gastrointestinal and genitourinary smooth muscle. Life Sci. 64 403. PMID: 10069503. Pfaffet al (1995) The (S)-(+)-enantiomer of dimethindene: a novel M2-selective muscarinic receptor antagonist. Eur.J.Pharmacol. 286 229. PMID: 8608784. |