| 货号 | 3870/50 |
| 别名 | (S*,R*)-2-[(4-Hydroxy-4-phenyl-1-pi |
| 供应商 | Tocris |
| 生物活性 | Selective sigma (σ) receptor ligand. Displays high affinity for σ1; also binds at σ2 sites (Ki = 1.5 nM and 50.8 nM respectively). Selective over a range of receptor types including dopaminergic and muscarinic receptors, DAT and SERT. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 469.53 |
| 分子式 | C24H29NO3.C2H2O4 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 10 mM in ethanol |
| CAS号 | 932736-90-8 |
| 参考文献 | Antoniniet al (2009) Anti-amnesic properties of (±)-PPCC, a novel sigma receptor ligand, on cognitive dysfunction induced by selective cholinergic lesion in rats. J.Neurochem. 109 744. PMID: 19245662. Prezzaventoet al (2008) A new sigma ligand, (±)-PPCC, antagonizes kappa opioid receptor-mediated antinociceptive effect. Life Sci. 82 549. PMID: 18261749. Prezzaventoet al (2007) Novel sigma receptor ligands: synthesis and biological profile. J.Med.Chem. 50 951. PMID: 17328523. |