货号 | 1317/50 |
别名 | 5-Propoxy-3-(1,2,3,6-tetrahydro-4-p |
供应商 | Tocris |
生物活性 | Potent, selective 5-HT1B agonist (Ki values are 89, 2, 860, 49 and 1,600 nM for 5-HT1A, 5-HT1B, 5-HT1C, 5-HT1D and 5-HT2 receptors respectively). Centrally active upon systemic administration in vivo. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >98 % |
计算分子量 | 293.8 |
分子式 | C15H19N3O.HCl |
可溶性/溶解性 | Soluble to 25 mM in water and to 100 mM in DMSO |
CAS号 | 131084-35-0 |
参考文献 | Knobelmanet al (2000) Regulation of extracellular concentrations of 5-hydroxytryptamine (5-HT) in mouse striatum by 5-HT1A and 5-HT1B receptors. J.Pharmacol.Exp.Ther. 292 1111. PMID: 10688630. Fishet al (1999) Aggression heightened by alcohol or social instigation in mice: reduction by the 5-HT(1B) receptor agonist CP-94,253. Psychopharmacology 146 391. PMID: 10550489. Koeet al (1992) Biochemical and behavioral studies of the 5-HT1B receptor agonist, CP-94,253. Drug Dev.Res. 26241. |