Iromycin A
货号：
19621-5mg 基本售价：
9786.0 元 规格：
5 mg
产品信息
概述| 货号 | 19621-5mg |
| 描述 | Iromycin A is a bacterial pyridone metabolite that inhibits nitric oxide synthase (NOS) activity, with selectivity for NOS III (endothelial NOS) over NOS I (neuronal NOS).1,2 Iromycin metabolites and derivatives block NADH oxidation in beef heart submitochondrial particles (IC50 = 0.461 µM for iromycin A).3 |
| 别名 | NK 26588; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Shojaei, H.,Li-Böhmer, Z. and von Zezschwitz, P. Iromycins: A new family of pyridone metabolites from Streptomyces sp. II. Convergent total synthesis. The Journal of Organic Chemistry 72(14), 5091-5097 (2007).
2.Surup, F.,Wagner, O.,von Frieling, J., et al. The iromycins, a new family of pyridone metabolites from Streptomyces sp. I. Structure, NOS inhibitory activity, and biosynthesis. The Journal of Organic Chemistry 72(14), 5085-5090 (2007).
3.Surup, F.,Shojaei, H.,von Zezschwitz, P., et al. Iromycins from Streptomyces sp. and from synthesis: New inhibitors of the mitochondrial electron transport chain. Bioorganic & Medicinal Chemistry 16(4), 1738-1746 (2008).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 303.4 |
| 分子式 | C19H29NO2 |
| CAS号 | 213137-53-2 |
| 稳定性 | ≥ 1 year |
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