| 货号 | 5903/50 |
| 别名 | (S)-3-(2-(3-Chlorophenyl)acetamido) |
| 供应商 | Tocris |
| 生物活性 | FFA2 antagonist/inverse agonist (pKi = 7.87). Selective for human over mouse FFA2. Increases forskolin-induced cAMP production and inhibits acetate-induced MAPK signaling in cells expressing human FFA2. |
| 运输条件 | Ambient |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 399.79 |
| 分子式 | C19H17ClF3NO |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 50 mM in ethanol |
| 参考文献 | Parket al (2016) Selective novel inverse agonists for human GPR43 augment GLP-1 secretion. Eur.J.Pharmacol. 771 1. PMID: 26683635. Sergeevet al (2016) Non-equivalence of key positively charged residues of the free fatty acid 2 receptor in the recognition and function of agonist versus antagonist ligands. J.Biol.Chem. 291 303. PMID: 26518871. |