SR 0987 ( )
货号：
5868/50 基本售价：
9745.9 元 规格：
50 mg
产品信息
概述| 货号 | 5868/50 |
| 别名 | 2-Chloro-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]benzamide |
性能| 供应商 | Tocris |
| 生物活性 | T cell-specific RORγ(RORγt) agonist (EC50 = 800 nM in a gene reporter assay). Induces IL-17 expression and decreases PD-1 expression in T cells in vitro. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 397.7 |
| 分子式 | C16H10ClF6NO |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| 参考文献 | Changet al (2016) Synthetic RORγt agonists enhance protective immunity. ACS Chem.Biol. 11 1012. PMID: 26785144. |
