STOCK2S 26016 ( )
货号：
5570/50 基本售价：
9745.9 元 规格：
50 mg
产品信息
概述| 货号 | 5570/50 |
| 别名 | 7-Ethoxy-N3-(2-furanylmethyl)-3,9-acridinediamine |
性能| 供应商 | Tocris |
| 生物活性 | Lysine deficient protein kinase (WNK) signaling inhibitor (IC50 = 16 μM). Inhibits binding of WNK1 and WNK4 to SPAK and phosphorylation of downstream transporters, NKCC1 and NCC, in mouse vascular smooth muscle and distal convoluted tubule cell cultures exposed to hypotonic shock, respectively. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 333.38 |
| 分子式 | C20H19N3O2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 50 mM in ethanol |
| 参考文献 | Moriet al (2013) Chemical library screening for WNK signalling inhibitors using fluorescence correlation spectroscopy. Biochem.J. 455 339. PMID: 23981180. |
