| 货号 | 18178-10mg |
| 描述 | Dynorphin B is a 13-residue opioid peptide released from the cleavage of prodynorphin and found widely distributed in the central nervous system.1,2 It acts as a κ1b-opioid receptor agonist (Ki = 1.1 nM) and has been implicated in antinociceptive functions.3 Dynorphin B has also been used to prime cardiogenesis in pluripotent embryonic stem cells.4 |
| 别名 | Dynorphin B-13;Rimorphin; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Berman, Y.,Juliano, L., and Devi, L.A. Specificity of the dynorphin-processing endoprotease: comparison with prohormone convertases. Journal of Neurochemistry 72, 2120-2196 (1999). 2.Janecka, A.,Fichna, J., and Janecki, T. Opioid receptors and their ligands. Current Topics in Medicinal Chemistry 4, 1-17 (2004). 3.Dhawan, B.N.,Cesselin, F.,Raghubir, R., et al. International Union of Pharmacology. XII. Classification of opioid receptors. Pharmaceutical Research 48(4), 567-592 (1996). 4.Ventura, C.,Zinellu, E.,Maninchedda, E., et al. Dynorphin B is an agonist of nuclear opioid receptors coupling nuclear protein kinase C activation to the transcription of cardiogenic genes in GTR1 embryonic stem cells. Circulation Research 92, 623-629 (2003). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 1570.8 |
| 分子式 | C74H115N21O17 |
| CAS号 | 83335-41-5 |
| 稳定性 | ≥ 2 years |
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