| 货号 | 1245/50 |
| 别名 | (3-Aminopropyl)(diethoxymethyl)phos |
| 供应商 | Tocris |
| 生物活性 | Selective, brain penetrant GABAB receptor antagonist (IC50 = 34 μM as measured in rat cortical membranes). Has higher affinity for postsynaptic versus presynaptic receptors. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 225.22 |
| 分子式 | C8H20NO4P |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 123690-79-9 |
| 参考文献 | Staubliet al (1999) GABAB receptor antagonism: facilitatory effects on memory parallel those on LTP induced by TBS but not HFS. J.Neurosci. 19 4609. PMID: 10341258. Sutor and Luhmann (1998) Involvement of GABAB receptors in convulsant-induced epileptiform activity in rat neocortex in vitro. Eur.J.Neurosci. 10 3417. PMID: 9824455. Haoet al (1994) Intrathecal γ-aminobutyric acidB(GABAB) receptor antagonist CGP 35348 induces hypersensitisation to mechanical stimuli in the rat. Neurosci.Lett. 182 299. PMID: 7715832. Olpeet al (1990) CGP 35348: a centrally active blocker of GABAB receptors. Eur.J.Pharmacol. 187 27. PMID: 2176979. |