KN-92 (hydrochloride)
货号：
9000890-10mg 基本售价：
9632.0 元 规格：
10 mg
产品信息
概述| 货号 | 9000890-10mg |
| 描述 | KN-92 is an inactive derivative of KN-93, the selective inhibitor of Ca2+/calmodulin-dependent kinase type II (CaMKII).1 At concentrations up to 25 μM, KN-92 is ineffective at inhibiting CaMKII or arresting cell growth of NIH 3T3 fibroblasts.2 It is intended to be used as a control compound in studies designed to elucidate the antagonist activities of KN-93 (Item No. 13319). |
性能| 供应商 | Cayman |
| 应用文献 |
1.Sumi, M.,Kiuchi, K.,Ishikawa, T., et al. The newly synthesized selective Ca2+/calmodulin dependent protein kinase II inhibitor KN-93 reduces dopamine contents in PC12th cells. Biophys. Res. Commun. 181(3), 968-975 (1991).
2.Tombes, R.M.,Grant, S.,Westin, E.H., et al. G1 cell cycle arrest and apoptosis are induced in NIH 3T3 cells by KN-93, an inhibitor of CaMK-II (the multifunctional Ca2+/CaM kinase). Cell Growth & Differentiation 6(9), 1063-1070 (1995).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 493.4 |
| 分子式 | C24H25ClN2O3S • HCl |
| CAS号 | 1431698-47-3 |
| 稳定性 | ≥ 2 years |
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