| 货号 | 21801-10mg |
| 描述 | 10,11-dehydro Curvularin is a natural mycotoxin that has cytotoxic activity against select cancer cell lines.1,2 It has been shown to activate the heat shock response, block TGF-β signaling, and scavenge superoxide anions.1,3,4 |
| 别名 | α,β-dehydro Curvularin; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Kumar, C.G.,Mongolla, P.,Sujitha, P., et al. Metabolite profiling and biological activities of bioactive compounds produced by Chrysosporium lobatum strain BK-3 isolated from Kaziranga National Park, Assam, India. Springerplus 2(1), 122 (2013). 2.Zhan, J.,Wijeratne, E.M.,Seliga, C.J., et al. A new anthraquinone and cytotoxic curvularins of a Penicillium sp. from the rhizosphere of Fallugia paradoxa of the Sonoran desert. J. Antibiot. (Tokyo) 57(5), 341-344 (2004). 3.Rudolph, K.,Serwe, A., and Erkel, G. Inhibition of TGF-β signaling by the fungal lactones (S)-curvularin, dehydrocurvularin, oxacyclododecindione and galiellalactone. Cytokine 61(1), 285-296 (2013). 4.Xu, Y.,Espinosa-Artiles, P.,Schubert, V., et al. Characterization of the biosynthetic genes for 10,11-dehydrocurvularin, a heat shock response-modulating anticancer fungal polyketide from Aspergillus terreus. Appl. Environ. Microbiol. 79(6), 2038-2047 (2013). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 290.3 |
| 分子式 | C16H18O5 |
| CAS号 | 21178-57-4 |
| 稳定性 | ≥ 2 years |
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