Aurora Kinase Inhibitor II
货号：
17541-10mg 基本售价：
9604.0 元 规格：
10 mg
产品信息
概述| 货号 | 17541-10mg |
| 描述 | The Aurora kinases are a family of serine/threonine kinases that are key regulators of mitosis and cytokinesis. Aurora kinase inhibitor II is a cell-permeable anilinoquinazoline that blocks the activity of Aurora A (IC50 = 0.39 µM).1 In MCF-7 cells, it blocks proliferation with an IC50 value of 1.25 µM.1 |
| 别名 | 4-(4ʹ-Benzamidoanilino)-6,7-dimethoxyquinazoline; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Heron, N.M.,Anderson, M.,Blowers, D.P., et al. SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors. Bioorganic & Medicinal Chemistry Letters 16(5), 1320-1323 (2006).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 400.4 |
| 分子式 | C23H20N4O3 |
| CAS号 | 331770-21-9 |
| 稳定性 | ≥ 2 years |
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