Nexturastat A
货号：
16874-10mg 基本售价：
9604.0 元 规格：
10 mg
产品信息
概述| 货号 | 16874-10mg |
| 描述 | Nexturastat A is a potent inhibitor of HDAC6 (IC50 = 5.02 nM) that displays high selectivity over all other HDACs.1 It dose-dependently induces hyperacetylation of α-tubulin in B16 murine melanoma cells without elevating histone H3 acetylation.1 Nexturastat A is cell-permeable and inhibits the proliferation of B16 cells (GI50 = 14.3 µM).1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Bergman, J.A.,Woan, K.,Perez-Villarroel, P., et al. Selective histone deacetylase 6 inhibitors bearing substituted urea linkers inhibit melanoma cell growth. Journal of Medicinal Chemistry 55(22), 9891-9899 (2012).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 341.4 |
| 分子式 | C19H23N3O3 |
| CAS号 | 1403783-31-2 |
| 稳定性 | ≥ 2 years |
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