VU 591 hydrochloride (50 MG)
货号：
4197/50 基本售价：
9597.2 元 规格：
50 mg
产品信息
概述| 货号 | 4197/50 |
| 别名 | 6-Nitro-2-[(6-nitro-1H-benzimidazol-2-yl)methoxymethyl]-1H-benzimidazole hydrochloride |
性能| 供应商 | Tocris |
| 生物活性 | Selective renal outer medullary potassium channel (Kir1.1, ROMK) antagonist (IC50 = 300 nM). Thought to block the intracellular pore of the Kir1.1 channel. Exhibits no effect on Kir7.1 at concentrations up to 10 μM; does not inhibit Kir2.1, Kir2.3 or Kir4.1. Displays similar potency to VU 590 (Cat. No. 3891). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 404.76 |
| 分子式 | C16H12N6O5 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Bhaveet al (2011) Development of a selective small-molecule inhibitor of Kir1.1, the renal outer medullary potassium channel. Mol.Pharmacol. 79 42. PMID: 20926757. |
