SLV 320 (50 MG)
货号:
3344/50 基本售价:
9597.2 元 规格:
50 mg
产品信息
概述货号 | 3344/50 |
别名 | trans-4-[(2-Phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexanol |
性能供应商 | Tocris |
生物活性 | Potent and selective adenosine A1 receptor antagonist (Ki values are 1, 200, 398 and 3981 nM at human A1, A3, A2A and A2B receptors respectively). Suppresses cardiac fibrosis and attenuates albuminuria, without effect on blood pressure in animal models of chronic renal failure. Orally active. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >99 % |
计算分子量 | 308.38 |
分子式 | C18H20N4O |
可溶性/溶解性 | Soluble to 100 mM in DMSO and to 50 mM in ethanol |
CAS号 | 251945-92-3 |
参考文献 | Kalket al (2007) The adenosine A1 receptor antagonist SLV320 reduces myocardial fibrosis in rats with 5/6 nephrectomy without effecting blood pressure. Br.J.Pharmacol. 151 1025. PMID: 17558436. |