RETRA hydrochloride (50 MG)
货号：
3214/50 基本售价：
9597.2 元 规格：
50 mg
产品信息
概述| 货号 | 3214/50 |
| 别名 | 2-[(4,5-Dihydro-2-thiazolyl)thio]-1-(3,4-dihydroxyphenyl)ethanone hydrochloride |
性能| 供应商 | Tocris |
| 生物活性 | Antitumor agent. Inhibits tumor cell growth in a mutant p53- and p73-dependent manner in vitroandin vivo(IC50 = 4 μM). Transcriptionally activates expression of p53-responsive genes and induces activation of effector caspases 3 and 7. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 305.8 |
| 分子式 | C11N11NO3S2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 1036069-26-7 |
| 参考文献 | Kravchenkoet al (2008) Small-molecule RETRA suppresses mutant p53-bearing cancer cells through a p73-dependent salvage pathway. Proc.Natl.Acad.Sci.USA 1056302. |
